CIAPM Request for Proposals 2019 - FAQs

I represent a research team that has not previously received funds from CIAPM, but we are housed within a university/institution that is currently funded (from the 2018 RFP). Is my team eligible to apply for this funding opportunity?

Yes, any new team would be eligible and highly encouraged to submit a proposal. CIAPM will not accept proposals from previously or currently funded teams, but other research teams from previously funded institutions are very welcome.

Does a teaching hospital that conducts medical research meet the definition of an "academic research institution"?

Yes, accredited teaching hospitals that conduct medical research are eligible to serve as the "Primary Institution."

Must a project community partner be non-profit?

At least one PI on the proposal must represent a non-profit community/patient organization or county health institution that provides support to people with ACEs.

What are the instructions for the format and contents of the Full Proposal (Stage 3)?

Instructions for composing and submitting full proposals will be provided to finalists by May 28, 2020. Institutional cover letters will be required for full proposal submission. The submission deadline for Full Proposals is July 22, 2020.

What are the selection criteria for the full proposals?

The selection criteria are posted on the website and will not differ throughout the selection process, from concept proposal review and full proposal review.

How can I access the Informational Webinar?

If you were unable to join live, you may still view a recording of the webinar. Science Officer Julianne McCall provided background on Precision Medicine and ACEs, discussed the community-researcher partnership component, and presented additional parameters. Attendees were invited to ask questions in writing during the webinar and by email beforehand.

Can project teams include multiple community organizations as partners?

Absolutely! ACEs is a complex field that requires many partners with different perspectives and areas of expertise.

What is the source of funding for this Request for Proposals (RFP)?

Funding for this RFP is provided by the State of California and administered by the Governor’s Office of Planning and Research (OPR).

How should proposal materials be submitted?

All proposal materials must be submitted electronically in PDF format by the Lead Principle Investigator (Lead PI) via the CIAPM Submission Portal. Applications may be re-opened (even after clicking the “Submit” button) any time prior to the submission deadline.

Will the Letter of Intent be scored by the Selection Committee?

No. The Letters of Intent will be used exclusively to inform CIAPM staff of the optimal composition of the Selection Committee, in order to cover as many areas of expertise as are presented among the complete portfolio of proposals.

May I change some project details between the submission of the Letter of Intent and the submission of the Concept Proposal?

Yes, however, the Lead PI must not change and the general theme of the project must remain intact.

Does the RFP limit the number of proposals each institution may submit?

This RFP does not limit the number of proposals each institution may submit or otherwise be included in as a partner. However, not more than one project will be awarded per Primary Institution (primary affiliation of the Lead Principle Investigator).

What institutions are eligible to participate?

The RFP requires that application teams include, at a minimum, Principle Investigators (PIs) from two types of institutions: 1) public or private academic research institutions and 2) nonprofit community/patient organizations or county institutions that provide services to people with ACEs. The institution of the Lead PI is considered the Primary Institution and must be a public or private academic research institution. Other PIs, project team members, and key collaborators may be affiliated with any type of public or private entity within California, such as tribal organizations, health care providers, private industry, education systems, and venture capital.

What counts as a nonprofit patient/community organization or county institution that provides care to people with ACEs?

Examples of eligible nonprofit institutions include patient advocacy organizations, community organizations that coordinate services for adults and/or children with ACEs, community clinics and hospitals, county health and behavioral health agencies, and Federally Qualified Health Centers that provide services to people with ACEs. CIAPM does not intend to be overly proscriptive of qualifying institutions.

What is the Precision Medicine Asset Inventory?

The CIAPM website includes a new, interactive mapping tool, called the “California Precision Medicine Asset Inventory” for members of any organization relevant to health, healthcare, and health equity to better understand the landscape of California-based researchers, community organizations, clinicians, industry, datasets, and other resources relevant to Precision Medicine. Many applicants may find the platform helpful for searching for potential research partners. If you are interested in having your information as an individual and/or organization posted to this platform, please submit the CIAPM Asset Inventory Survey.

Can CIAPM assist me in finding collaborators for my proposal?

Teams seeking project collaborators should directly contact potential partners to gauge their interest. The CIAPM team is also available to facilitate connections, whether for the development of proposals, the strengthening of proposals after the concept proposal submission deadline, or otherwise. Any other inquiries about how the CIAPM team can help facilitate collaborations can also be sent to CIAPM staff.

What are the restrictions on proposal budgets?

Proposals should not include any indirect costs. CIAPM has not identified any additional budget item restrictions but reserves the right to make determinations on a case-by-case basis. If a concept proposal includes a budget item that CIAPM deems to be ineligible for use of CIAPM funds, the CIAPM team will contact the project team and ask for the item to be excluded if the team is invited to submit a full proposal. The inclusion of a budget item deemed to be ineligible will not adversely impact the proposal in the concept proposal selection process. Please direct any questions about specific budget items to CIAPM staff.

Should I include in my proposal the development of a data sharing platform?

The RFP describes that funds may become available for awarded project teams to examine and potentially select and use a common data-sharing platform. This step will occur following the selection of demonstration projects; selected project teams will work together to explore what is possible to share across projects and potentially scale beyond them. This step will occur regardless of how many awarded projects include their own data sharing platform components, so proposals may include the development and use of common data sharing platforms across project partners. If so, please describe why this is beneficial to the project, how it is distinctive, and whether it might be scalable, and include funding for the data sharing component in the budget. However, since there is limited space to explain your project in the concept proposal, it is advisable to not devote too much of it to the data sharing component.

What factors will the Selection Committee consider during the final decision process?

The authorizing statute identifies a breadth of possible focus areas for proposals to improve health outcomes for patient populations with ACEs backgrounds, as listed in the RFP. These focus areas and selection criteria are reflective of the diverse fields and goals that comprise precision medicine. In order to maximize the overall impact of the funded portfolio of projects, the Selection Committee will select a balanced portfolio that represents diversity in several areas, including but not limited to, approaches, research focus areas, patient populations, host institutions, and partners during its deliberations. Thus, while selecting highly meritorious proposals based on final overall impact scores of the individual proposals, the Selection Committee will take into consideration these factors when making funding recommendations to OPR. Finally, as required by statute, the Selection Committee will ensure the inclusion of host institutions in both northern and southern California.

Will project teams that include individuals/institutions that have already been granted CIAPM funds be viewed less favorably than others?

No. Prior receipt of CIAPM funds will not be a consideration in the demonstration project selection process.